Old Main, Bethany College is a historic building group on the Bethany College campus in Bethany, West Virginia.

Bethany is a town in southern Brooke County, West Virginia, United States. The population was 756 at the 2020 census. It is part of the Weirton–Steubenville metropolitan area. It is best known as the home of Bethany College, a private liberal arts college that was the first institution of higher education in what is now West Virginia.