The Old San Antonio Road was a historic roadway located in the U.S. states of Texas and Louisiana. Parts of it were based on traditional Native American trails. Its Texas terminus was about 35 miles (56 km) southeast of Eagle Pass at the Rio Grande in Maverick County, and its northern terminus was at Natchitoches, Louisiana. The road continued from Texas through Monclova to Mexico City.

Maverick County is a county located in the U.S. state of Texas. As of the 2020 census, its population was 57,887. Its county seat is Eagle Pass. The county was created in 1856 and organized in 1871. It is named for Samuel Maverick, cattleman and state legislator.