Old Town Pizza is a pizzeria established in 1974 and located in the historic Merchant Hotel building in the Old Town Chinatown neighborhood of central Portland, Oregon in the United States. The company has a satellite location at Vanport Square in Northeast Portland that includes a brewery branded as Old Town Brewing Co. Two days before its March 2012 opening, a fire forced the restaurant to undergo reconstruction for six weeks.

The Merchant Hotel, also known as the Merchants' Hotel, is a historic former hotel building in Portland, Oregon, United States. It is located at 121 N.W. Second Avenue in Old Town Chinatown. It is a contributing property in the Portland Skidmore/Old Town Historic District, which was listed on the U.S. National Register of Historic Places in 1975 and designated a National Historic Landmark District in 1977. It is one of the few remaining examples of Victorian Italianate, cast iron architecture on the West Coast. It occupies half of a city block, specifically along the south side of N.W. Davis Street from Second to Third Avenues.