Oncogene
Videos
An oncogene is a gene that has the potential to cause cancer. In tumor cells, these genes are often mutated, or expressed at high levels.
Illustration of how a normal cell is converted to a cancer cell, when an oncogene becomes activated
HER2
Videos
Receptor tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. ERBB is abbreviated from erythroblastic oncogene B, a gene origin
1n8z: Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab
1s78: Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex