Oncolytic virus
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An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release new infectious virus particles or virions that h
Viral luciferase expression in a mouse tumour
Vaccinia virus infected cells expressing beta-glucuronidase (blue colour)
Adenoviral NIS gene expression in a mouse tumour (Located at the crosshairs) following intravenous delivery of virus (Left) compared to an uninfected control mouse (Right)
Lysis
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Lysis is the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic mechanisms that compromise its integrity. A fluid containing the contents of lysed cells is called a lysate. I
Oncolytic virus
…An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release new infectious virus particles or virions that help destroy the remaining tumour. Oncolytic viruses are thought not only to cause direct…
Plasmolysis