Oncometabolism
Videos
Oncometabolism is the field of study that focuses on the metabolic changes that occur in cells that make up the tumor microenvironment and accompany oncogenesis and tumor progression toward a neoplast
Otto Heinrich Warburg, considered the "Father of Oncometabolism" for his early discoveries in the field
Acetyl-CoA
Videos
Acetyl-CoA is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism. Its main function is to deliver the acetyl group to the citric acid cycle to be
Oncometabolism
…which is reached through defects in enzymes involved in normal cell metabolism, this allows the cancer cells to meet their energy needs and divert acetyl-CoA from the TCA cycle to build essential biomolecules such as amino acids and lipids. These defects cause an overabundance of endogenous metabolites, which…
β-Oxidation of fatty acids