Opera Fusion: New Works (OF:NW) is a partnership between Cincinnati Opera and the University of Cincinnati College-Conservatory of Music (CCM) dedicated to fostering the development of new American operas. This collaboration is jointly led by Evans Mirageas, the Harry T. Wilks Artistic Director at Cincinnati Opera, as well as Robin Guarino, Professor of Opera at CCM. Since its founding in 2011, OF:NW has developed twenty-three new American operas. From the program's inception in 2011 through 2022, co-founders Marcus Küchle and Guarino served as co-artistic directors.

Cincinnati Opera is an American opera company based in Cincinnati, Ohio and the second oldest opera company in the United States. Beginning with its first season in 1920, Cincinnati Opera has produced operas in the summer months of June and July with the Cincinnati Symphony Orchestra providing orchestral accompaniment.