Operation Burnt Frost was a military operation to intercept and destroy non-functioning U.S. National Reconnaissance Office (NRO) satellite USA-193. The mission was described by the Missile Defense Agency as a "mission of safeguarding human life against the uncontrolled re-entry of a 5,000-pound satellite containing over 1,000 pounds of hazardous hydrazine propellant". The launch occurred on 21 February 2008 at approximately 10:26 p.m. EST from the USS Lake Erie, using a heavily modified Standard Missile-3 (SM-3) to shoot down the satellite. A few minutes after launch, the SM-3 intercepted its target and successfully completed its mission. The operation received scrutiny from other countries, mainly China and Russia.

USA-193, also known as NRO Launch 21, was a United States military reconnaissance satellite launched on 14 December 2006. It was the first launch conducted by the United Launch Alliance (ULA). Owned by the National Reconnaissance Office (NRO), the craft's precise function and purpose were classified. On 21 February 2008, it was destroyed as a result of Operation Burnt Frost.