Opernhaus Wuppertal is a German theatre in Wuppertal, North Rhine-Westphalia. It houses mostly performances of operas, but also plays, run by the municipal Wuppertaler Bühnen. The house is also the venue for dance performances by the Tanztheater Wuppertal company created by Pina Bausch.

Wuppertal is a city in North Rhine-Westphalia, Germany, with a population of 355,000. Wuppertal is the seventh-largest city in North Rhine-Westphalia and 17th-largest in Germany. It was founded in 1929 by the merger of Elberfeld, Barmen, Ronsdorf, Cronenberg and Vohwinkel, and was initially "Barmen-Elberfeld" before adopting its present name in 1930. It is the capital and largest city of the Bergisches Land.