The Ophites, also called Ophians, were a Christian Gnostic sect depicted by Hippolytus of Rome (170–235) in a lost work, the Syntagma ("arrangement").
The Brazen Serpent (illustration from a Bible card published 1907 by Providence Lithograph Company)
Agnolo Bronzino, Il serpente di bronzo, from the chapel of Eleonora of Toledo, Firenze, Palazzo Vecchio
William Blake, The Temptation and Fall of Eve, 1808 (illustration of Milton's Paradise Lost)
Gnosticism is a collection of religious ideas and systems that coalesced in the late 1st century AD among Jewish and early Christian sects. These various groups emphasized personal spiritual knowledge (gnosis) above the proto-orthodox teachings, traditions, and authority of religious institutions.
Page from the Gospel of Judas
Mandaean Beth Manda (Mashkhanna) in Nasiriyah, southern Iraq in 2016, a contemporary-style mandi
A lion-faced deity found on a Gnostic gem in Bernard de Montfaucon's L'antiquité expliquée et représentée en figures may be a depiction of Yaldabaoth, the Demiurge; however, see Mithraic Zervan Akarana.
Mandaeans in prayer during baptism