Oregon Route 99E is an Oregon state highway that runs between Junction City, Oregon and an interchange with I-5 just south of the Oregon/Washington border, in Portland. It, along with OR 99W, makes up a split of OR 99 in the northern part of the state. This split existed when the route was U.S. Route 99, when the two branches were U.S. 99W and U.S. 99E.

Albany is the county seat of Linn County, Oregon, and is the 11th most populous city in the state. Albany is located in the Willamette Valley at the confluence of the Calapooia River and the Willamette River in both Linn and Benton counties, just east of Corvallis and south of Salem. It is predominantly a farming and manufacturing city that settlers founded around 1848. As of the 2020 United States Census, the population of Albany, Oregon was 56,472.