The Oregon and California Railroad was formed from the Oregon Central Railroad when it was the first to operate a 20-mile (32 km) stretch south of Portland in 1869. This qualified the railroad for land grants in California, whereupon the name of the railroad soon changed to Oregon & California Rail Road Company. In 1887, the line was completed over Siskiyou Summit, and the Southern Pacific Railroad assumed control of the railroad, although it was not officially sold to Southern Pacific until January 3, 1927. This route was eventually spun off from the Southern Pacific as the Central Oregon and Pacific Railroad.

Drain is a city in Douglas County, Oregon, United States. The population was 1,151 at the 2010 census. Drain is named after town founder and politician Charles J. Drain, who donated 60 acres (24 ha) of nearby land to the Oregon and California Railroad in 1871.