In molecular biology, Ornithine decarboxylase antizyme is an ornithine decarboxylase inhibitor. It binds to, and destabilises, ornithine decarboxylase, a key enzyme in polyamine synthesis. ODC is then
NMR structure of antizyme isoform 1 from rat
Messenger RNA
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Messenger ribonucleic acid is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein.
Ornithine decarboxylase antizyme
…is modulated according to the cellular concentration of polyamines. High levels of polyamines induce a +1 ribosomal frameshift in the translation of mRNA for the antizyme leading to the expression of a full-length protein. At least two forms of ODC-AZ exist in mammals and the protein has been found in…
Universal structure of eukaryotic mRNA, showing the structure of the 5' and 3' UTRs.
mRNA circularization and regulation
Overview of mRNA decay pathways in the different life domains.