Orono is a town in Penobscot County, Maine, United States. Located on the Penobscot and Stillwater rivers, it was first settled by American colonists in 1774. They named it in honor of Chief Joseph Orono, a sachem of the indigenous Penobscot nation who long occupied this territory.

Penobscot County is a county in the U.S. state of Maine, named for the Penobscot people in Wabanakik. As of the 2020 census, the population was 152,199, making it the third-most-populous county in Maine. Its county seat is Bangor. The county was established on February 15, 1816, from part of Hancock County when the area was still part of Massachusetts. Penobscot County is home to the University of Maine.