Orphan: First Kill is a 2022 American psychological horror film directed by William Brent Bell, written by David Coggeshall, based on a story by David Leslie Johnson-McGoldrick and Alex Mace. It is a prequel to the 2009 film Orphan. It stars Isabelle Fuhrman, Julia Stiles, Rossif Sutherland, Hiro Kanagawa, and Matthew Finlan.

William Brent Bell is an American film director, screenwriter, and producer. He is known for his work on horror films such as Stay Alive (2006), The Devil Inside (2012), Wer (2013), The Boy (2016), Brahms: The Boy II (2020), Separation (2021), Orphan: First Kill (2022), and Lord of Misrule (2023). His films have grossed over $300 million worldwide at the box office.