The House of Ostrogski was one of the more prominent families in the Kingdom of Poland, the Grand Duchy of Lithuania and in the Polish–Lithuanian Commonwealth. The family spanned from the 14th century Ruthenian noble Daniil Ostrogski to the 17th century Polish members. After the death of Janusz Ostrogski, the last male heir, most of the family's possessions passed to the Zasławski family.

Prince Janusz Ostrogski was a Polish-Lithuanian noble and statesman. He served as a voivode of Volhyn (1584-1593), as a castellan of Kraków, and as a starosta of Bohuslav, Biała Cerkiew, Czerkasy and Kaniów, Perejasław and Włodzimierz.