Otisco is a town in Onondaga County, New York, United States. As of the 2020 Census, the population was 2,368. Otisco is in the southwestern part of the county, situated at the northern edge of the Appalachian Highlands, where an escarpment declines to the Lake Ontario plain and the city of Syracuse five miles to the north.

Pompey is a town in the southeast part of Onondaga County, New York. As of the 2020 Census, the population was 7,080. The town was named after the Roman general and political leader Pompey by a late 18th-century clerk interested in the Classics in the new federal republic.