Our Lady of Solitude is a title of Mary, mother of Jesus and a special form of Marian devotion practised in Spanish-speaking countries to commemorate the solitude of Mary on Holy Saturday. Variant names include Nuestra Señora de la Soledad, Maria Santisima, Nuestra Señora Dolorosisima de la Soledad, and Virgen de la Soledad.

Mission Nuestra Señora de la Soledad, commonly known as Mission Soledad, is a Spanish mission located in Soledad, California. The mission was founded by the Franciscan order on October 9, 1791, to convert the Native Americans living in the area to Catholicism. It was the thirteenth of California's Spanish missions, and is named for Mary, Our Lady of Solitude. The town of Soledad is named for the mission.