The Ouse Valley Railway was to have been part of the London, Brighton & South Coast Railway (LBSCR). It was authorised by an Act of Parliament in 1864 and construction of the 20 miles (32 km) long line was begun, but not completed. It never opened to traffic.

The London, Brighton and South Coast Railway was a railway company in the United Kingdom from 1846 to 1922. Its territory formed a rough triangle, with London at its apex, practically the whole coastline of Sussex as its base, and a large part of Surrey. It was bounded on its western side by the London and South Western Railway (L&SWR), which provided an alternative route to Portsmouth. On its eastern side the LB&SCR was bounded by the South Eastern Railway (SER)—later one component of the South Eastern and Chatham Railway (SE&CR)—which provided an alternative route to Bexhill, St Leonards-on-Sea, and Hastings. The LB&SCR had the most direct routes from London to the south coast seaside resorts of Brighton, Eastbourne, Worthing, Littlehampton and Bognor Regis, and to the ports of Newhaven and Shoreham-by-Sea. It served the inland towns and cities of Chichester, Horsham, East Grinstead and Lewes, and jointly served Croydon, Tunbridge Wells, Dorking and Guildford. At the London end was a complicated suburban and outer-suburban network of lines emanating from London Bridge and Victoria, and shared interests in two cross-London lines.