Owyhee is a census-designated place (CDP) in Elko County, Nevada, United States, along the banks of the Owyhee River. The population was 953 at the 2010 census. It is part of the Elko Micropolitan Statistical Area. It is the primary town of the federally recognized Shoshone-Paiute tribe's Duck Valley Indian Reservation, which covers portions of northern Nevada and southern Idaho, and the majority of its population are Native American.

Elko County is a county in the northeastern corner of Nevada, United States. As of the 2020 census, the population was 53,702. Its county seat is Elko. The county was established on March 5, 1869, from Lander County.