PD-L1
Videos
Programmed death-ligand 1 also known as cluster of differentiation 274 or B7 homolog 1 is a protein that in humans is encoded by the CD274 gene.
Figure 3. Evolution of PD-1 and its interacting molecules.
Binding interactions
Micrograph showing a PD-L1 positive lung adenocarcinoma. PD-L1 immunostain
Durvalumab
Videos
Durvalumab, sold under the brand name Imfinzi, is an anti-cancer medication used for treatment of various types of cancer. It was developed by Medimmune/AstraZeneca. It is a human immunoglobulin G1 ka
PD-L1
…PD-L1 inhibitors are in development as immuno-oncology therapies and are showing good results in clinical trials. Clinically available examples include durvalumab, atezolizumab and avelumab. In normal tissue, feedback between transcription factors like STAT3 and NF-κB restricts the immune response to protect host…
Immunotherapy: mechanism of action for Durvalumab, Pembrolizumab, Ipilimumab, Atezolizumab.