Progress Multi Trade Air Flight 241 was a scheduled domestic passenger flight from Siem Reap to Sihanoukville, Cambodia. The flight was operated by regional airliner PMTair using an Antonov An-24. On 25 June 2007, the Antonov An-24, registered as XU-U4A, disappeared over the Cambodian jungle near Bokor Mountain in Kampot while on approach to Sihanoukville. A massive search and rescue operation ensued with thousands of soldiers and police scoured the area. The aircraft was found to have crashed in southwestern Cambodia, northeast of Dâmrei Mountains. All 22 people on board, most of whom were South Korean tourists, were killed. It remains as the second deadliest air disaster in Cambodian history.

Sihanouk International Airport, located 20 kilometres (12 mi) east of Sihanoukville City in Sihanoukville Province, is Cambodia's third largest international airport. It is named, like the province itself, after King Norodom Sihanouk. The airport is also known as Kang Keng Airport. The IATA code KOS is derived from Sihanoukville's alternative name "Kampong Som".