The Padmanabhaswamy Temple is a Hindu temple dedicated to Vishnu in Thiruvananthapuram, the capital of the state of Kerala, India. It is one of the 108 Divya Desams which are considered the sacred abodes of Vishnu in the Sri Vaishnava tradition. The name of the city of 'Thiruvananthapuram' in Malayalam and Tamil translates to "The City of Ananta". The temple is built in an intricate fusion of the Kerala style and the Dravidian style of architecture, featuring high walls, and a 16th-century gopuram. While as per some traditions the Ananthapura temple in Kumbla in Kasaragod district in Kerala is considered as the original spiritual seat of the deity ("Mulasthanam"), architecturally to some extent, the temple is a replica of the Adikesava Perumal temple in Thiruvattar in Kanyakumari district in Tamil Nadu. It is widely considered the world's richest Hindu temple.

Thiruvananthapuram, commonly shortened to TVM or by its former name Trivandrum, is the capital city of the Indian state of Kerala. It is the most populous city in Kerala with a population of 957,730 as of 2011. The encompassing urban agglomeration population is around 1.68 million. Located on the west coast of India near the extreme south of the mainland, Thiruvananthapuram is a major information technology hub in Kerala and contributes 55% of the state's software exports as of 2016. Referred to by Mahatma Gandhi as the "Evergreen city of India", the city is characterised by its undulating terrain of low coastal hills.