Paducah is a home rule-class city in and the county seat of McCracken County, Kentucky, United States. The largest city in the Jackson Purchase region, it is located in the Southeastern United States at the confluence of the Tennessee and the Ohio rivers, halfway between St. Louis, Missouri, to the northwest and Nashville, Tennessee, to the southeast. As of the 2020 census, the population was 27,137, up from 25,024 in 2010. Twenty blocks of the city's downtown have been designated as a historic district and listed on the National Register of Historic Places.

McCracken County is a county located in the far west portion of U.S. state of Kentucky. As of the 2020 census, the population was 67,875. The county seat and only municipality is Paducah. McCracken County was the 78th county formed in the state, having been created in 1825. It is part of the historic Jackson Purchase, territory sold by the Chickasaw people to General Andrew Jackson and Governor Isaac Shelby; this territory was located at the extreme western end of Kentucky.