Hotel Plaza Grande is a five-star luxury hotel in the historic centre of Quito, Ecuador. The hotel is located next to the Carondelet Palace and the Archbishop's Palace and faces the Old Town's eponymous central plaza, Plaza de la Independencia. It is located in a restored Spanish colonial mansion, which formerly belonged to one of the earliest colonial inhabitants of Quito, Juan Diaz de Hidalgo.

Carondelet Palace is the seat of government of the Republic of Ecuador, located in Quito. Access is by the public space known as Independence Square or Plaza Grande, around which are also the Archbishop's Palace, Municipal Palace, Hotel Plaza Grande, and Metropolitan Cathedral.