The Palais des Papes is a historical palace located in Avignon, Southern France. It is one of the largest and most important medieval Gothic buildings in Europe. Once a fortress and palace, the papal residence was a seat of Western Christianity during the 14th century. Six papal conclaves were held in the Palais, leading to the elections of Benedict XII in 1334, Clement VI in 1342, Innocent VI in 1352, Urban V in 1362, Gregory XI in 1370 and Benedict XIII in 1394. Since 1995, the Palais des Papes has been classified, along with the historic center of Avignon, as a UNESCO World Heritage Site, for its outstanding architecture and historical importance for the papacy.

Avignon is the prefecture of the Vaucluse department in the Provence-Alpes-Côte d'Azur region of southeastern France. Located on the left bank of the river Rhône, the commune had a population of 93,671 as of the census results of 2017, with about 16,000 living in the ancient town centre enclosed by its medieval walls. It is France's 35th-largest metropolitan area according to INSEE with 337,039 inhabitants (2020), and France's 13th-largest urban unit with 459,533 inhabitants (2020). Its urban area was the fastest-growing in France from 1999 until 2010 with an increase of 76% of its population and an area increase of 136%. The Communauté d'agglomération du Grand Avignon, a cooperation structure of 16 communes, had 197,102 inhabitants in 2022.