The Palestinian General Federation of Trade Unions (PGFTU), also called the Palestine General Federation of Trade Unions or Palestinian Trade Union Federation, is a national trade union center in the Palestinian Territories. It has an estimated membership of 290,000, and is affiliated with the International Trade Union Confederation. The union in its current form is historically aligned with Fatah, but other parties have also worked within its organization.

Histadrut, or the General Organization of Workers in Israel, originally, is Israel's national trade union center and represents the majority of Israel's trade unionists.