Palmyra is an ancient city in the eastern part of the Levant, now in the center of modern Syria. Archaeological finds date back to the Neolithic period, and documents first mention the city in the early second millennium BC. Palmyra changed hands on a number of occasions between different empires before becoming a subject of the Roman Empire in the first century AD.

Syria or Sham is a historical region located east of the Mediterranean Sea in West Asia, broadly synonymous with the Levant. Other synonyms are Greater Syria or Syria-Palestine. The region boundaries have changed throughout history. However, in modern times, the term "Syria" alone is used to refer to the Syrian Arab Republic.