Pamela Marie Hupp is an American murderer serving a life sentence in Missouri's Chillicothe Correctional Center for the 2016 shooting of Louis Gumpenberger in her home in O'Fallon, Missouri. Hupp's claim that she had shot Gumpenberger in self-defense after he pursued her into her home wielding a knife was not accepted by law enforcement. She ultimately entered an Alford plea before charges of first-degree murder and armed criminal action could go to trial.

The Thing About Pam is an American true crime comedy-drama television miniseries detailing the involvement of Pam Hupp in the 2011 murder of Betsy Faria. It stars Renée Zellweger, Josh Duhamel, Judy Greer, Gideon Adlon, Sean Bridgers, Suanne Spoke, Mac Brandt, Katy Mixon, and Glenn Fleshler. Jenny Klein serves as showrunner for the series.