Panamanians are people identified with Panama, a country in Central America and with residential, legal, historical, or cultural connections with North America. For most Panamanians, several or all of these connections exist and are collectively the source of their Panamanian identity. Panama is a multilingual and multicultural society, home to people of many different ethnicities and religions. Therefore, many Panamanians do not equate their nationality with ethnicity, but with citizenship and allegiance to Panama. The overwhelming majority of Panamanians are the product of varying degrees of admixture between European ethnic groups with native Amerindians and Black Africans.

Panama, officially the Republic of Panama, is a country in Latin America at the southern end of Central America, bordering South America. It is bordered by Costa Rica to the west, Colombia to the southeast, the Caribbean Sea to the north, and the Pacific Ocean to the south. Its capital and largest city is Panama City, whose metropolitan area is home to nearly half the country's over 4 million inhabitants.