The Pancho Villa Expedition—now known officially in the United States as the Mexican Expedition, but originally referred to as the "Punitive Expedition, U.S. Army"—was a military operation conducted by the United States Army against the paramilitary forces of Mexican revolutionary Francisco "Pancho" Villa from March 14, 1916, to February 7, 1917, during the Mexican Revolution of 1910–1920.

The Second Battle of Agua Prieta, 1 November 1915, was fought between the forces of Pancho Villa and those of the future President of Mexico, Plutarco Elías Calles, a supporter of Venustiano Carranza, at Agua Prieta, Sonora, as part of the Mexican Revolution. Villa's attack on the town was repulsed by Calles. The battle helped to establish Carranza's control over Mexico and directly led to his becoming, with United States recognition, president. Villa believed that Calles had received tactical and strategic support from the United States since the town is located across the border from Douglas, Arizona and launched his raid on Columbus, New Mexico partly as a reprisal.