Panelefsiniakos F.C., the Panelefsiniakos Athletic Club, is a football club based in the city of Elefsina, Greece. The club currently competes in Football League. The team was formed in 1931.

Elefsina or Eleusis is a suburban city and municipality in Athens metropolitan area. It belongs to West Attica regional unit of Greece. It is located in the Thriasio Plain, at the northernmost end of the Saronic Gulf. North of Elefsina are Mandra and Magoula, while Aspropyrgos is to the northeast.