The Papez circuit, or medial limbic circuit, is a neural circuit for the control of emotional expression. In 1937, James Papez proposed that the circuit connecting the hypothalamus to the limbic lobe
In a dissected brain, the inferior medial view shows the curved shape of the structures of the Papez circuit in the human brain.
A heuristic model of the neural pathway of the Papez circuit shows the connections between its different parts.
Compared to a healthy individual, Alzheimer's patients experience significantly more brain loss. The neurodegenerative effects of the disease can be seen by comparing the brains of a healthy individual and an Alzheimer's patient.
Neuroscientist Paul D. MacLean is famous for his work on the limbic system and its evolutionary history.
The subiculum also known as the subicular complex, or subicular cortex, is the most inferior component of the hippocampal formation. It lies between the entorhinal cortex and the CA1 hippocampal subfi
Papez circuit
…indicates that the average size of the circuit is 350 millimeters. The Papez circuit goes through the following neural pathways: Hippocampal formation (subiculum) → fornix → mammillary bodies → mammillothalamic tract → anterior thalamic nucleus → cingulum → entorhinal cortex → hippocampal formation. A photograph…
Subiculum labeled at center left (coronal brain slice).
CA1 transition to subiculum Artist Don Cooper and Leah Leverich