Parasite Eve is a Japanese science fiction horror novel by Hideaki Sena, first published by Kadokawa in 1995. The book was published in North America by Vertical, Inc. in 2005.

Parasite Eve is a 1998 survival horror action role-playing video game developed and published by Square. The game is a sequel to the novel Parasite Eve, written by Hideaki Sena; it is the first game in the Parasite Eve video game series. The story follows New York City police officer Aya Brea over a six-day span in 1997 as she attempts to stop the Eve, a woman who plans to destroy the human race through spontaneous human combustion. Players explore levels set in areas of New York while utilizing a pausable real-time combat system along with several role-playing elements.