The railway from Paris-Est to Strasbourg-Ville is a 493-kilometre-long railway line that connects Paris to Strasbourg via Châlons-en-Champagne and Nancy, France. Officially, the line does not start at the Gare de l'Est in Paris: the first 9 km until Noisy-le-Sec is shared with the railway from Paris to Mulhouse. The railway was opened in several stages between 1849 and 1852. The opening of the LGV Est high speed line from Paris to Baudrecourt in Lorraine in 2007 has decreased the importance of the section Paris–Sarrebourg for passenger traffic.

The Strasbourg–Wörth railway is a French-German railway, which runs in the French region of Grand Est and the German state of Rhineland-Palatinate.