The Parma–La Spezia railway is the railway line that connects Parma, Italy with the Genoa–Pisa railway near La Spezia over the Cisa Pass through the Apennines. The route is approximately 120 kilometres long. Its Italian name derives from the town of Pontremoli, one of the main towns it passes through.

The Genoa–Pisa railway is one of the trunk lines of the Italian railway network. It runs along the Ligurian coast from Genoa to Pisa through the Riviera di Levante and the Versilia. It passes through the cities of Massa, Carrara and La Spezia. South of Pisa the Pisa–Rome line continues along the Tyrrhenian coast to Rome. The line is double track and is fully electrified at 3,000 V DC. Passenger traffic is managed by Trenitalia.