Pasquotank County High School is a school in Elizabeth City, Pasquotank County, North Carolina, USA. PCHS's mascot is the Panther. Its school colors are navy blue and silver. It is one of three high schools in the Elizabeth City-Pasquotank Public Schools system; the other is Northeastern High School. PCHS was established in 2000 to relieve the population of Northeastern High; however, all members of the senior class of 2001 remained at Northeastern, making the class of 2002 the first graduating class of Pasquotank County High. The class of 2004 was the first group of students to start at the school as freshmen and graduate from there, spending all four years as PCHS Panthers.

Elizabeth City is a city in Pasquotank and Camden counties, North Carolina, United States. As of the 2020 census, it had a population of 18,629. Elizabeth City is the county seat and most populous city of Pasquotank County. It is the cultural, economic and educational hub of the sixteen-county Historic Albemarle region of northeastern North Carolina.