Patch clamp
Videos
The patch clamp technique is a laboratory technique in electrophysiology used to study ionic currents in individual isolated living cells, tissue sections, or patches of cell membrane. The technique i
A bacterial spheroplast patched with a glass pipette
Patch clamp of a nerve cell within a slice of brain tissue. The pipette in the photograph has been marked with a slight blue color.
Bert Sakmann
Videos
Bert Sakmann is a German cell physiologist. He shared the Nobel Prize in Physiology or Medicine with Erwin Neher in 1991 for their work on "the function of single ion channels in cells," and the inven
Patch clamp
…membrane is controlled by the experimenter and the resulting changes in voltage are recorded, generally in the form of action potentials. Erwin Neher and Bert Sakmann developed the patch clamp in the late 1970s and early 1980s. This discovery made it possible to record the currents of single ion channel molecules for…
Sakmann