The Pechanga Resort Casino is a Native American casino on the Pechanga Indian Reservation adjacent to the city of Temecula, California. Pechanga Resort Casino is one of the largest casino/resorts in the United States, with more than 5,400 slot machines and approximately 200,000 sq ft (19,000 m2) of gaming space.

Native American gaming comprises casinos, bingo halls, slots halls and other gambling operations on Indian reservations or other tribal lands in the United States. Because these areas have tribal sovereignty, states have limited ability to forbid gambling there, as codified by the Indian Gaming Regulatory Act of 1988. As of 2011, there were 460 gambling operations run by 240 tribes, with a total annual revenue of $27 billion.