The Peggy Guggenheim Collection is an art museum on the Grand Canal in the Dorsoduro sestiere of Venice, Italy. It is one of the most visited attractions in Venice. The collection is housed in the Palazzo Venier dei Leoni, an 18th-century palace, which was the home of the American heiress Peggy Guggenheim for three decades. She began displaying her private collection of modern artworks to the public seasonally in 1951. After her death in 1979, it passed to the Solomon R. Guggenheim Foundation, which opened the collection year-round from 1980.

The Grand Canal is a channel in Venice, Italy. It forms one of the major water-traffic corridors in the city.