Pennsylvania Route 225 is a 48.5-mile-long (78.1 km) state highway located in Dauphin and Northumberland Counties in Pennsylvania. The southern terminus is at an interchange with U.S. Route 22 /US 322 in Dauphin. The northern terminus is at PA 61 in Shamokin. PA 225 is mostly a two-lane undivided road running through mountain and valley areas in the central part of the state. The route serves the communities of Halifax, Elizabethville, Berrysburg, Pillow, and Trevorton. PA 225 intersects PA 325 north of Dauphin, PA 147 in Halifax, US 209 in Elizabethville, PA 25 in Berrysburg, and PA 890 in Trevorton.

Dauphin is a borough in Dauphin County, Pennsylvania, United States. The population was 796 at the 2020 census. Dauphin's ZIP code is 17018. It is part of the Harrisburg–Carlisle Metropolitan Statistical Area.