Pennsylvania Route 255 is a 39.7-mile-long (63.9 km) state highway located in Clearfield and Elk counties in Pennsylvania. The southern terminus is at U.S. Route 219 in DuBois. The northern terminus is at US 219 in Johnsonburg.

Clearfield County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 80,562. The county seat is Clearfield, and the largest city is DuBois. The county was created in 1804 and later organized in 1822.