Pennsylvania Route 340 (PA 340) is a 30-mile-long (48 km) state highway located in Lancaster and Chester counties in Pennsylvania. The western terminus is at PA 462 in Lancaster. The eastern terminus is at U.S. Route 30 Business in Thorndale. The route is a two-lane road passing through rural areas, heading through the Pennsylvania Dutch Country in eastern Lancaster County that is home to several Amish families and rural areas in western Chester County, serving the communities of Bird-in-Hand, Intercourse, White Horse, Compass, and Wagontown. PA 340 intersects US 30 near Lancaster, PA 772 in Intercourse, PA 897 in White Horse, PA 10 in Compass, PA 82 near Coatesville, and US 30 again near Thorndale.

Pennsylvania Route 462 is a 32-mile-long (51 km) east–west state route in York and Lancaster counties in central Pennsylvania. The western terminus is west of York, and the eastern terminus is east of Lancaster. At both ends, PA 462 terminates at U.S. Route 30, which follows a mostly freeway alignment parallel to the north between York and Lancaster. The route heads east into York, where it follows the one-way pair of Market Street eastbound and Philadelphia Street westbound. In York, PA 462 runs concurrent with PA 74 and crosses Interstate 83 Business. East of York, the route becomes a multilane road that has an interchange with I-83 and crosses PA 24. PA 462 continues east through Hallam to Wrightsville and passes through that town before it crosses the Susquehanna River and runs through Columbia. East of here, the route continues through Mountville before reaching the city of Lancaster. In Lancaster, PA 462 is routed on the one-way pair of King Street eastbound and Walnut Street westbound, with the westbound direction concurrent with PA 23. The route crosses US 222/PA 272 and northbound PA 72 in Lancaster. East of Lancaster, PA 462 becomes a multilane road again and continues to its eastern terminus.