Pennsylvania Route 414 is a 79.4-mile-long (127.8 km) state highway located in Lycoming, Tioga, and Bradford counties in Pennsylvania. The western terminus is at PA 44 in Waterville. The eastern terminus is at US 220 in Monroe. The first leg of the highway, between its intersection with PA 44 in Waterville and Blackwell is very narrow and rugged.

Tioga County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 41,045. Its county seat is Wellsboro. The county was created on March 26, 1804, from part of Lycoming County and later organized in 1812. It is named for the Tioga River. The county is part of the North Central Pennsylvania region of the state.