Pennsylvania Route 472 is a north–south state highway in Chester and Lancaster counties in Pennsylvania. Its southern terminus is at PA 841 in Lewisville 300 yards (270 m) north of the Maryland border. Its northern terminus is at PA 372 in Quarryville. PA 472 is a two-lane undivided road that passes through mostly rural areas along a northwest-southeast alignment. The route passes through the borough of Oxford, where it intersects the southern terminus of PA 10 and has an interchange with U.S. Route 1. PA 472 was originally designated in 1928 between US 1/PA 12/PA 42 in Oxford and PA 372 in Quarryville. The route was extended south to Hickory Hill by 1930, at which time the entire length of the route was paved. The southern terminus of PA 472 was extended to PA 841 in Lewisville in 1937.

Chester County, colloquially referred to as Chesco, is a county in the Commonwealth of Pennsylvania. It is located in the Delaware Valley region, located in the southeastern part of the state. As of the 2020 census, the population was 545,823(As of 2022), increasing by 7.1% from 498,886 in 2010. The county seat is the Borough of West Chester. The most populous of its 73 municipalities is Tredyffrin Township. The most populous boroughs are West Chester and Phoenixville. Coatesville is the only municipality in the County organized under the City form of government, a technical rather than demographic distinction. Chester County was one of the three original Pennsylvania counties created by William Penn in 1682. It was named for Chester, England. The county is part of the Southeast Pennsylvania region of the state.