Pennsylvania Route 563 (PA 563) is a state highway in the U.S. state of Pennsylvania. The route runs 21.15 mi (34.04 km) from PA 63 in Upper Salford Township northeast to PA 412 in Nockamixon Township. The road runs through mostly rural areas in the northern parts of Montgomery and Bucks counties. Along the way, the route passes through the northern part of Perkasie and forms a concurrency with PA 313 in East Rockhill Township. North of here, PA 563 runs through Nockamixon State Park, heading to the northwest of Lake Nockamixon.

Pennsylvania Route 63 (PA 63) is a 37.4-mile-long (60.2 km) state highway located in the Philadelphia, Pennsylvania, area. The western terminus of the route is at PA 29 in Green Lane, Montgomery County. The eastern terminus is at Interstate 95 (I-95) in Bensalem Township, Bucks County. PA 63 runs northwest to southeast for most of its length. The route heads through a mix of suburban and rural areas of northern Montgomery County as a two-lane road, passing through Harleysville, before coming to an interchange with I-476 in Kulpsville. From this point, PA 63 continues through predominantly suburban areas of eastern Montgomery County as a two- to four-lane road, passing through Lansdale, Maple Glen, Willow Grove, and Huntingdon Valley. Upon entering Northeast Philadelphia, the route follows Red Lion Road and U.S. Route 1 (US 1) before heading southeast on a freeway called Woodhaven Road to I-95.