Pennsylvania Route 568 is an 11.60-mile-long (18.67 km) state route in Berks County in east central Pennsylvania, United States. The western terminus is at U.S. Route 222 near Adamstown, where PA 568 continues to the southwest as PA 272. The eastern terminus is at PA 724 in the Robeson Township hamlet of Gibraltar. The route is a two-lane undivided road that passes through rural areas in southern Berks County. The route intersects PA 625 in Knauers, passes through Alleghenyville, and forms a brief concurrency with PA 10 in Green Hills. PA 568 was designated onto its current alignment by 1966. The intersection with US 222 and PA 272 at the western terminus was replaced with an interchange in 2006.

Berks County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the county's population was 428,849. The county seat is Reading, the fourth-most populous city in the state. The county is part of the South Central Pennsylvania region of the state.