Pennsylvania Route 63 (PA 63) is a 37.4-mile-long (60.2 km) state highway located in the Philadelphia, Pennsylvania, area. The western terminus of the route is at PA 29 in Green Lane, Montgomery County. The eastern terminus is at Interstate 95 (I-95) in Bensalem Township, Bucks County. PA 63 runs northwest to southeast for most of its length. The route heads through a mix of suburban and rural areas of northern Montgomery County as a two-lane road, passing through Harleysville, before coming to an interchange with I-476 in Kulpsville. From this point, PA 63 continues through predominantly suburban areas of eastern Montgomery County as a two- to four-lane road, passing through Lansdale, Maple Glen, Willow Grove, and Huntingdon Valley. Upon entering Northeast Philadelphia, the route follows Red Lion Road and U.S. Route 1 (US 1) before heading southeast on a freeway called Woodhaven Road to I-95.

Pennsylvania Route 29 is a 118-mile-long (190 km) north–south state highway that runs through most of eastern Pennsylvania.