Pennsylvania Route 663 (PA 663) is a 22.13-mile-long (35.61 km) state highway in Montgomery and Bucks counties in southeast Pennsylvania. Its southern terminus is at PA 100 in the borough of Pottstown and its northern terminus is at PA 309 and PA 313 in the borough of Quakertown, where the road continues eastward as PA 313. Along the way, PA 663 also passes through the borough of Pennsburg. It is called John Fries Highway between Pennsburg and Quakertown. It has an interchange with Interstate 476 at exit 44 west of Quakertown. The route was assigned in 1930, and it has had several realignments since its commissioning, including two major ones.

Pennsylvania Route 100 is a 59.4-mile (95.6 km) long state highway in the U.S. state of Pennsylvania that runs from U.S. Route 202 near West Chester north to PA 309 in Pleasant Corners. The route runs between the western suburbs of Philadelphia and the Lehigh Valley region of the state, serving Chester, Montgomery, Berks, and Lehigh counties. PA 100 intersects several important highways, including US 30 in Exton, the Pennsylvania Turnpike (Interstate 76, near Lionville, US 422 near Pottstown, US 222 in Trexlertown, and I-78/US 22 in Fogelsville. Several sections of PA 100 are multi-lane divided highway with some interchanges, including between US 202 and the Pennsylvania Turnpike in Chester County between south of Pottstown and New Berlinville, and between Trexlertown and Fogelsville.