Pennsylvania Route 739 is a Pennsylvania highway contained entirely within Pike County, Pennsylvania. It was signed in 1967, and runs for 19 miles (31 km). Its northern terminus is at U.S. Route 6 in Blooming Grove, running south to US 209 in Delaware Township. PA 739's southern end is at the Dingman's Ferry Bridge at the Delaware River near Layton, New Jersey. It continues as County Route 560 in New Jersey.

Pike County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 58,535. Its county seat is Milford. The county is part of the Northeast Pennsylvania region of the state.